The Histological Analysis of Implantable Medical Devices
Resin/Plastic Sectioning vs Cutting and Grinding
Resin/plastic histology is typically used to examine hard tissue such as bone and implanted medical device interaction with surrounding tissues. There are two basic methodologies: grinding, also called cutting and grinding, and sectioning, which is done on a rotary microtome. In either method, samples are first dehydrated then infiltrated with a plastic monomer which is subsequently polymerized into a plastic tissue block. Each method offers its own unique advantages and disadvantages. Resin/plastic histology is more labour intensive than paraffin histology and processing is usually conducted manually due to required lengthy resin infiltration times.
- Why More Organizations are Outsourcing Histopathology
- Fixation and Shipment of Wet Tissues for Paraffin Embedding Downstream Services
- Fixation and Shipment of Tissue Samples for Frozen Downstream Applications
- Advantages and Drawbacks of Paraffin and Frozen Tissues
- Histopathology for Oncology Therapeutics
- Resin Histology by Device Type (Cut & Grind vs. Microtomy)
- Histopathological Considerations for IHC-based Studies
- Fixing Tissue for Optimal Results: Part II
- Fixing Tissue for Optimal Results: Part 1
- Conducting an IHC Study - Factors to Consider: Part II
- Conducting an IHC Study - Factors to Consider: Part 1
- The Histological Analysis of Implantable Medical Devices
- Conducting Biocompatibility Testing for a Medical Device: Part II
- Conducting Biocompatibility Testing for a Medical Device: Part I
- Challenges Faced by Medical Device Companies: Part II
- Challenges Faced by Medical Device Companies: Part I
- Biocompatibility of Implants/Medical Devices
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